Methoxybenzoic acids and derivatives
Medchemexpress LLC Hydroxy-PEG4-acid 10g | 937188-59-5 | 10 G
Hydroxy-PEG4-acid is a four-unit polyethylene glycol (PEG) linker with a terminal hydroxyl and a carboxylic acid, supplied as a purified reagent for bioconjugation and linker synthesis. It is suitable for use as a non-cleavable spacer in antibody-drug conjugates (ADCs), and as a PEG-based linker in PROTACs and related chemistries.
- Four-unit PEG spacer with terminal hydroxyl and carboxylic acid.
- High purity suitable for research use.
- Available in multiple pack sizes, including 10 G.
- Stable when stored at recommended temperatures for long-term use.
- Useful for ADC linker construction, PROTAC assembly, and general bioconjugation.
Medchemexpress LLC 5-Methoxy-a-ethyltry 10mM 1mL | 4765-10-0 | 218.29 g/mol | C13H18N2O | 1 ML
5-Methoxy-α-ethyltryptamine (5-MeO-α-ET; CAS 4765-10-0) is a tryptamine-class research compound supplied as a solid and as a 10 mM solution in DMSO for laboratory use. Molecular formula C13H18N2O; molecular weight 218.29 g/mol. For research use only; not for human consumption.
- Chemical name: 5-methoxy-α-ethyltryptamine (CAS 4765-10-0).
- Molecular formula: C13H18N2O.
- Molecular weight: 218.29 g/mol.
- Purity: 98.9% (as listed on COA).
- Formulation: solid and 10 mM solution in DMSO (1 ml).
- Storage: in solution store at -80°C up to 6 months or -20°C short term; protect from light.
- Intended use: supplied for in vitro research applications.
eMolecules ChemScene / 4-Methoxybenzoic acid phenyl ester / 250mg / 572307753 / CS-W001020 / 0.000 / 4181-97-9 / MFCD00443298 / 228.247 / C14H12O3
ChemScene / 4-Methoxybenzoic acid phenyl ester / 250mg / 572307753 / CS-W001020 / 0.000 / 4181-97-9 / MFCD00443298 / 228.247 / C14H12O3
Sigma Aldrich Fine Chemicals Biosciences 3-Methoxybenzoic acid ReagentPlus(R), 99% | 586-38-9 | MFCD00002499 | 100G
3-Methoxybenzoic acid ReagentPlus(R), 99% | Purity: 99% | Mol Wt: 152.15 | 586-38-9 | MFCD00002499 | 100G
Medchemexpress LLC Ro 08-2750 | 37854-59-4 | 98.01% | 270.24 | 10 MG
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor that binds to NGF with an IC50 of approximately 1 μM. It selectively inhibits NGF binding to p75NTR over TRKA. Ro 08-2750 is also a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM.
- Binds to the NGF dimer, potentially inducing a conformational change that prevents NGF from binding to p75NTR.
- Completely rescues cells from NGF-induced SK-N-MC 103 cell death at 10 nM.
- Increases differentiation and apoptosis in myeloid leukemia cells at 5-10 μM (8 hours).
- Inhibits survival of human AML lines and patient cells.
- Inhibits MSI2 RNA-binding and alters MSI2 gene signature.
- Inhibits leukemogenesis in a myeloid leukemia model in vivo at 13.75 mg/kg (i.p.).
- Reduces c-MYC levels and disease burden in a myeloid leukemia model.
eMolecules Key Organics/BIONET - Building Blocks 3 4-Difluoro-5-methylaniline 1mg 447296265 PS-11837 95 000 1505944-46-6 MFCD22490569 143 137 C7H7F2N
Key Organics/BIONET - Building Blocks 3 4-Difluoro-5-methylaniline 1mg 447296265 PS-11837 95 000 1505944-46-6 MFCD22490569 143 137 C7H7F2N
Sigma Aldrich Fine Chemicals Biosciences 4-Methoxybenzoic acid certified reference material, TraceCERT(R) | 100-09-4 | MFCD00002542 | 100MG
4-Methoxybenzoic acid certified reference material, TraceCERT(R) | Mol Wt: 152.15 | 100-09-4 | MFCD00002542 | 100MG
eMolecules 3-(Cyclopentyloxy)-5-(trifluoromethoxy)phenylboronic acid | 1256346-04-9 | MFCD16295065 | 1g
Combi-Blocks | 3-(Cyclopentyloxy)-5-(trifluoromethoxy)phenylboronic acid | 1g | 117524601 | BB-6377 | 97.000 | 1256346-04-9 | MFCD16295065 | 290.050 | C12H14BF3O4
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eMolecules 6-(Cyclopentyloxy)-2-fluoropyridine-3-boronic acid | 2096339-69-2 | 5G | Purity: 97%
Combi-Blocks | 6-(Cyclopentyloxy)-2-fluoropyridine-3-boronic acid | 5G | 2096339-69-2 | MFCD18434416
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eMolecules TERT-BUTYL 4-(3-METHOXYBENZOYL)PIPERAZINE-1-CARBOXYLATE | 1325340-60-0 | MFCD14635753 | 1g
AstaTech | TERT-BUTYL 4-(3-METHOXYBENZOYL)PIPERAZINE-1-CARBOXYLATE | 1g | 434268136 | 20996 | 95.000 | 1325340-60-0 | MFCD14635753 | 320.389 | C17H24N2O4
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Selleck Chemical LLC Angelic anhydride S3806-25mg
Angelic anhydride (2-Methylisocrotonic Anhydride (Z)-2-Methylbut-2-enoic anhydride) is a synthetic chemical and usually used in content determination assays and pharmacological experiments
Medchemexpress LLC Hydroxy-PEG1-acid 5g | 89211-34-7 | 5 G
Hydroxy-PEG1-acid is a single-unit polyethylene glycol (PEG1) linker with terminal hydroxyl and carboxylic acid groups. Supplied for research use as a non-cleavable ADC linker, it provides a short PEG spacer to improve solubility and spacing between an antibody and payload in antibody-drug conjugates.
- Non-cleavable single-unit PEG linker for ADC synthesis.
- Terminal hydroxyl and carboxylic acid functional groups for conjugation.
- Short PEG spacer to improve solubility and reduce aggregation.
- Typical purity around 95% and colorless to light yellow appearance.
- Available in small research pack sizes, including 5 G.